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BENZODEP TAB 5MG 30S

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BENZODEP TAB 5MG 30S

BENZODEP TAB 5MG 30S

BENZODEP 5MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Buspirone 5mg

MANUFACTURER: Zaka Healthcare

QUANTITY:

Pack of 30 tablets

INDICATION

Benzodep 5mg Tab is a non-benzodiazepine anxiolytic used for the short-term and long-term management of generalized anxiety disorder (GAD). Unlike benzodiazepines, it does not cause sedation, muscle relaxation, or physical dependence, making it suitable for patients who need prolonged anxiety management without the risks of dependence or withdrawal. It is particularly useful in elderly patients and those with a history of substance misuse.

MECHANISM OF ACTION

Buspirone is a partial agonist at 5-HT1A serotonin receptors and a moderate antagonist at dopamine D2 receptors. By activating presynaptic 5-HT1A receptors, it reduces serotonergic neuronal firing in the raphe nucleus, dampening anxiety-related serotonin activity. Its partial agonism at postsynaptic 5-HT1A receptors also contributes to its anxiolytic effect. Unlike benzodiazepines, buspirone does not interact with GABA receptors and therefore produces no sedation, cognitive impairment, or addiction.

DOSAGE AND ADMINISTRATION

•      Starting dose: 5mg two to three times daily

•      Dose may be increased by 5mg every 2 to 3 days as needed

•      Usual effective dose: 15mg to 30mg per day in divided doses

•      Maximum dose: 60mg per day

•      Full anxiolytic effect typically takes 2 to 4 weeks of continuous treatment

SIDE EFFECTS

Common:

•      Dizziness, headache

•      Nausea, dry mouth

•      Nervousness or excitement in early treatment

•      Light-headedness

Less common:

•      Tachycardia and palpitations

•      Confusion or difficulty concentrating

•      Serotonin syndrome when combined with other serotonergic agents

NOT RECOMMENDED IN

•      Known hypersensitivity to buspirone

•      Severe hepatic or renal impairment

•      Concurrent use with monoamine oxidase inhibitors (MAOIs) — risk of serotonin syndrome

•      Not effective for acute anxiety or panic attacks

DRUG INTERACTIONS

Buspirone is primarily metabolized by CYP3A4. Strong inhibitors of this enzyme such as itraconazole, erythromycin, nefazodone, and grapefruit juice can increase buspirone plasma concentrations significantly, raising the risk of side effects. Rifampicin and other CYP3A4 inducers can reduce buspirone efficacy. Co-administration with MAOIs is contraindicated due to the risk of serotonin syndrome. Buspirone can increase the sedative effects of alcohol and other CNS depressants, though to a lesser extent than benzodiazepines.

STORAGE INSTRUCTIONS

Store Benzodep 5mg tablets at room temperature between 15°C and 30°C. Protect from moisture and light. Keep in original packaging and out of reach of children.

WHERE TO BUY

Buy Benzodep 5mg Tab online from Dawa Healthcare Pharmacy, a trusted source for psychiatric and anxiety medications in Pakistan. Check the Benzodep 5mg Tab price in Pakistan and learn about Benzodep 5mg Tab uses from our expert team. Same-day delivery is available in Karachi. Dawa Healthcare Pharmacy provides nationwide delivery across Pakistan.

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BENZODEP TAB 5MG 30S—
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Description

BENZODEP 5MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Buspirone 5mg

MANUFACTURER: Zaka Healthcare

QUANTITY:

Pack of 30 tablets

INDICATION

Benzodep 5mg Tab is a non-benzodiazepine anxiolytic used for the short-term and long-term management of generalized anxiety disorder (GAD). Unlike benzodiazepines, it does not cause sedation, muscle relaxation, or physical dependence, making it suitable for patients who need prolonged anxiety management without the risks of dependence or withdrawal. It is particularly useful in elderly patients and those with a history of substance misuse.

MECHANISM OF ACTION

Buspirone is a partial agonist at 5-HT1A serotonin receptors and a moderate antagonist at dopamine D2 receptors. By activating presynaptic 5-HT1A receptors, it reduces serotonergic neuronal firing in the raphe nucleus, dampening anxiety-related serotonin activity. Its partial agonism at postsynaptic 5-HT1A receptors also contributes to its anxiolytic effect. Unlike benzodiazepines, buspirone does not interact with GABA receptors and therefore produces no sedation, cognitive impairment, or addiction.

DOSAGE AND ADMINISTRATION

•      Starting dose: 5mg two to three times daily

•      Dose may be increased by 5mg every 2 to 3 days as needed

•      Usual effective dose: 15mg to 30mg per day in divided doses

•      Maximum dose: 60mg per day

•      Full anxiolytic effect typically takes 2 to 4 weeks of continuous treatment

SIDE EFFECTS

Common:

•      Dizziness, headache

•      Nausea, dry mouth

•      Nervousness or excitement in early treatment

•      Light-headedness

Less common:

•      Tachycardia and palpitations

•      Confusion or difficulty concentrating

•      Serotonin syndrome when combined with other serotonergic agents

NOT RECOMMENDED IN

•      Known hypersensitivity to buspirone

•      Severe hepatic or renal impairment

•      Concurrent use with monoamine oxidase inhibitors (MAOIs) — risk of serotonin syndrome

•      Not effective for acute anxiety or panic attacks

DRUG INTERACTIONS

Buspirone is primarily metabolized by CYP3A4. Strong inhibitors of this enzyme such as itraconazole, erythromycin, nefazodone, and grapefruit juice can increase buspirone plasma concentrations significantly, raising the risk of side effects. Rifampicin and other CYP3A4 inducers can reduce buspirone efficacy. Co-administration with MAOIs is contraindicated due to the risk of serotonin syndrome. Buspirone can increase the sedative effects of alcohol and other CNS depressants, though to a lesser extent than benzodiazepines.

STORAGE INSTRUCTIONS

Store Benzodep 5mg tablets at room temperature between 15°C and 30°C. Protect from moisture and light. Keep in original packaging and out of reach of children.

WHERE TO BUY

Buy Benzodep 5mg Tab online from Dawa Healthcare Pharmacy, a trusted source for psychiatric and anxiety medications in Pakistan. Check the Benzodep 5mg Tab price in Pakistan and learn about Benzodep 5mg Tab uses from our expert team. Same-day delivery is available in Karachi. Dawa Healthcare Pharmacy provides nationwide delivery across Pakistan.

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